Ceramide AP

Ceramide AP, also known as Ceramide 6-II, is a synthetic analog of naturally occurring ceramides found in the skin’s outermost layer (stratum corneum). Structurally, it features a phytosphingosine backbone linked to an alpha-hydroxy fatty acid, which imparts both powerful barrier-reinforcing and mild exfoliating properties. Ceramide AP excels at rebuilding and strengthening the skin barrier, reducing transepidermal water loss, and enhancing hydration by filling intercellular spaces and organizing surrounding lipids into functional layers. Its unique structure allows for deeper penetration and improved affinity with the skin’s lipid matrix, making it particularly effective for compromised, mature, or environmentally damaged skin. In addition to supporting barrier repair, Ceramide AP helps regulate cell turnover, lessens fine lines and wrinkles, calms inflammation, and protects against external stressors such as pollution and UV exposure. It is commonly found in moisturizers, serums, and repair creams, often alongside cholesterol, fatty acids, and other ceramides for optimal barrier support and hydration.